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 Built on two decades of scientific research in photobiology and DNA repair, Remergent is the next generation in skincare therapies. Applying biotechnology—in the form of patented liposome delivery systems—to biomimetic and select botanical ingredients, Remergent formulas are uniquely positioned to get active components into skin cells to repair damage, restore healthy response, and resist future injury.
Hydroquinone USP 4%]
Intense Bleaching Cream
Remergent™ HQ is indicated for the gradual treatment of ultraviolet-induced dyschromia, including photo-aging, solar and senile lentigenes, as well as discoloration resulting from the use of oral contraceptives, pregnancy, hormone replacement therapy, or skin trauma.
Active Ingredient:
Hydroquinone 4%
A highly effective hydroxyphenolic compound that interferes with melanin synthesis by inhibiting tyrosinase and other melanocyte metabolic processes.
Safety Information:
As a depigmenting agent, hydroquinone can cause sun sensitivity and exposure to sunlight or ultraviolet light will cause repigmentation. A sunscreen of at least SPF 30 should be used with this product.
Adverse effects include the development of inflammation and irritation, which may result in transient skin reddening and a mild burning sensation that do not preclude treatment.
Hydroquinone is usually formulated in an acidic base which may further irritation and can exacerbate hyperpigmentation resulting from skin trauma, e.g., post-inflammatory hyper pigmentation.
DNA Science for Skin Platform
Developed by Dr. Daniel B. Yarosh, a molecular biologist with a specialty in gene repair, Remergent is backed by better than twenty years of research and clinical study. Dr. Yarosh, who gained experience as an expert in DNA repair at the National Cancer Institute in Bethesda, Maryland, pioneered the development of a unique molecular delivery system. The patented technology is based on inserting repair enzymes into liposomes (nanometer lipid sacs) which are small, pure and agile enough to deliver payload ingredients at the cellular level.
Validated in controlled clinical studies and published in dozens of peer-reviewed scientific and medical journals, liposome-delivery is at the core of Remergent technology.
Damaging Effects of Sun on Skin
Exposure to ultraviolet light from sunlight accounts for nearly all of the symptoms of premature skin aging. Other skin changes, once believed to be caused by natural aging, are now known to be a result of prolonged exposure to UV radiation, called photoaging.
The ultraviolet radiation from the sun that reaches the earth's surface—and your skin—is divided into two categories: UVA and UVB, based on their wavelengths. The more energetic UVB rays are the primary agents for sunburn and do most of their damage in the uppermost layers of living skin. They have been closely linked to skin cancer. The far more abundant UVA rays have less energy but penetrate deeper into skin, exposing the underlying cells and supporting collagen fibers.
Both UVA and UVB cause damage to the skin's DNA, the master control for all the cell's functions. Damaged cells send out stress signals to other cells, and this begins a cascade of wounding responses that leads to premature aging. If the DNA damage is not repaired properly, the skin cell loses its ability to function correctly. Damaged cells may begin to divide and grow out of control, causing skin cancer.
The cascade of wounding responses has many effects on skin cells, structures and systems:
- Cells release enzymes that break down collagen at a faster rate, causing collagen fibers to fray. They separate from living cells, which makes the healing process more difficult. The result is a disorganized network of collagen fibers, known as solar scars. When the skin repeats this imperfect rebuilding process over years of sun exposure, wrinkles develop.
- Melanocytes are stimulated to make pigment (melanin) in the skin. In youth, for some, the result may be a tan. But during photoaging, the melanocytes lose their strict controls, and uneven pigmentation develops. This appears as light spots where melanocytes have stopped working or as dark brown areas, called age or sun spots, where they make too much melanin.
- Blood vessels the in the skin's surface permanently dilate and their walls thin. They appear as broken capillaries and spider veins (telangectasia).
- The upper layer of skin fills up with flaky dead layers that do not hold moisture. The skin appears sallow and dry, exaggerating the appearance of lines and wrinkles.
- Cells of the skin's immune system are suppressed, severely reducing their ability to eliminate damage or protect the skin from invading cells and toxins.
Key Performance Ingredients
 Merospheres.
Liposomes encapsulating ursolic acid, proven in clinical studies to prompt epidermal cells to accelerate lipid production and stimulate dermal fibroblasts to firm the collagen layer.
Formulated in:
 Photosomes.
Liposomes encapsulating a DNA repair enzyme from ocean plankton. Unique in their ability to harness light energy for defense, Photosomes have been proven in clinical research to improve the appearance of sun-damaged skin.
 Ultrasomes.
Liposomes engineered to carry an extract from a marine microbe, intensifying the skin's ability to repair sun-inflicted DNA damage, speeding recovery reaction, and reducing the appearance of post-sunburn peeling.
 Roxomes.
Liposomes encapsulating the first repair enzyme, isolated from a tiny mustard plant, to protect the cell's genetic material from free radical damage. Roxomes aid in the removal of oxidation in the cell's nucleus and its energy-generating mitochondria.
Formulated in:
 Pinoxide.
An exclusive and patented blend of breakthrough ingredients stimulating nitric oxide production to improve circulation. Clinical studies prove Pinoxide speeds blood flow, warms the skin, increases resistance to cold, and reduces dark under-eye symptoms.
Formulated in:
 Thiotaine.
A potent and stable lab-formulated replication of a botanical amino acid shown to promote skin energy and block the activation of two enzymes, elastase and matrix metalloproteinases (MMPs), which degrade collagen and elastin and destroy the skin's supporting structure, leading to wrinkle formation.
 VitAine.
Retinol, normally highly reactive, stabilized within a liposome delivery system for protection from inactivation by intercellular water molecules. Delivered into the cell, retinol is metabolized into retinoic acid, which increases skin thickness, reduces fine lines and wrinkles, and builds collagen for skin support.
Formulated in:
 Evodiox.
A biomimetic transcription of the ancient Chinese pain elixir Wu-Zhu-Yu, known to curb irritation and soothe aggravated skin. In clinical studies, the active components from the evodia fruit have been shown to inhibit inflammation and reduce stress.
 L-Ergothioneine.
An exclusive and maximized natural amino acid that prompts cells to respond on multiple levels to diminish the appearance of localized discolorations. Clinical studies prove L-Ergothioneine rapidly enables skin to achieve an even-toned skin appearance, without irritation.
 Vitamin C and Vitamin E
(in oil-soluble form).
Vitamin C, an essential for stimulating collagen production; Vitamin E, a natural regenerating partner, for maintaining vital antioxidant levels.
(Vitamin C only)
Merospheres®, Thiotaine®, Evodiox®, VitAine®, Photosomes®, Ultrasomes® and Roxomes® are registred trademarks of AGI Dermatics. Pinoxide™ is a trademark of AGI Dermatics.
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